The Poisoner's Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York

Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer

“The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times

“Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.”
—NPR: What We're Reading

A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice.

BUY THE BOOK

Published Jan 25, 2011

336 pages

Average rating: 7.5

46 RATINGS

|

These clubs recently read this book...

The Wanna Read Book Club

Because we wanna read all the books but we can’t.

Dorothy Parker Society - Seattle Chapter

A study group and book club centered around the wit of Dorothy Parker and the Algonquin Round Table Writers of the 1920s and beyond.

The Eclectic Reader Book Club

Our group of eclectic readers meets online twice a month to discuss books spanning a wide range of genres, time periods, and styles. All are welcome!

Community Reviews

anne ducastel
Jan 08, 2026
4/10 stars
I had high hopes with this book. Poisons and history, all written by a Pulizter Prize winner, I thought I was in for a treat. Sadly not, the writing was awkward and suffered from a typical case of "I've-done-all-that-research-and-I-have-to-put-it-in-somehow-even-if-it-does-not-quite-flow".
dnateach
Jan 01, 2026
10/10 stars
Loved this book!
Nina.bruja
Sep 28, 2024
10/10 stars
Loved this. A very interesting learning experience regarding the forensics and toxicology department in NYC during the 1920s.

See why thousands of readers are using Bookclubs to stay connected.