The Antidote: A Novel

NATIONAL BESTSELLER • FINALIST FOR THE NATIONAL BOOK AWARD • From Pulitzer finalist, MacArthur Fellowship recipient, and bestselling author of Swamplandia! and Vampires in the Lemon Grove Karen Russell: a gripping dust bowl epic about five characters whose fates become entangled after a storm ravages their small Nebraskan town

“Achingly gorgeous. . . . Karen Russell is one of our most humane and generous writers; this book is as profound as it is wonderfully strange.” Lauren Groff, author of The Vaster Wilds


The Antidote opens on Black Sunday, as a historic dust storm ravages the fictional town of Uz, Nebraska. But Uz is already collapsing—not just under the weight of the Great Depression and the dust bowl drought but beneath its own violent histories. The Antidote follows a "Prairie Witch,” whose body serves as a bank vault for peoples’ memories and secrets; a Polish wheat farmer who learns how quickly a hoarded blessing can become a curse; his orphan niece, a basketball star and witch’s apprentice in furious flight from her grief; a voluble scarecrow; and a New Deal photographer whose time-traveling camera threatens to reveal both the town’s secrets and its fate.

Russell's novel is above all a reckoning with a nation’s forgetting—enacting the settler amnesia and willful omissions passed down from generation to generation, and unearthing not only horrors but shimmering possibilities. The Antidote echoes with urgent warnings for our own climate emergency, challenging readers with a vision of what might have been—and what still could be.

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Published Mar 11, 2025

432 pages

Average rating: 7.54

56 RATINGS

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Courthouse Redemption

This is a no-stress, no-judgment book club that meets the first Wednesday of every month(ish), currently at Courthouse Brewing.

Community Reviews

Erick
Oct 20, 2025
10/10 stars
This is a beautiful book
SherylStandifer
Jul 19, 2025
9/10 stars
This is one of the best books I’ve read for awhile. I listened to it on audio, and it was produced with different voices for all the main voices - the Antidote herself, Antonina, the farmer, Harp Oletsky, the niece, Asphodel, and the photographer, Cleo Allfrey. And, the important side roles of cat and scarecrow. The real-life events of the Dust Bowl’s Black Sunday and the Republican River flood in 1935 inspired a convergence of strange events that defy logic in the story. Histories, both current and distant, play out with a woven storyline of conservation and ancestral rights to a place and time. Which, during the Dust Bowl era, became an indictment on imminent domain and whose rights became dominant, vs subdued. It gave the reader much to ponder.

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